Hi
I have several Desert Roses, which I was given by a lady at a hydroponics shop in the suburbs of Perth. She had lots of babies growing in a hydroponic solution with vermiculite as the medium.
The Desert Rose absolutely HATEs having its feet wet for an period longer than about 2 days. If they do get too wet the roots will immediately start to rot and you will then notice the stems and the body of the plant going soft and eventually dying.
I have mine in a 2 types of mixtures: one type is comprised of 4mm round gravel pebbles (available from Hydroponics stores the Big B only has larger sizes) and some (very little) sphagnum moss; the second mixture is comprised of Akadama and a small amount of sphagnum moss. I have found the sphagnum moss keeps sufficient moisture in the pot and limits the times you need to water.
I would be inclined to repot at the the beginning of spring, and as the plants flower around November/December, I would wait until after flowering to prune the plant.
Also, given the very softness of the branches, I think styling by clip and cut, rather than trying to wire the plant would be best - that is what I do.
As mentioned in the thread to the post referred to below, in Perth water, every second day (if they need it) and in winter move them to a warm spot away from the possibility of frost and give them a light watering every 2-3 weeks. Fertilize as per normal bonsai.
There has previously been a post on Adenium Obesiums and my reply to that post is at
viewtopic.php?f=104&t=804#p82364 . You will also find some more excellent information there as well.
Good luck
Michael
also, here is a photo of an Adenium that Jerry Meislik took in December 2009 at the 3rd Asia Pacific Bonsai Friendship Federation convention in Bangkok, Thailand. (referred to in the thread)